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MYP_151467
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Basic Information
Polybia-MPII
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
14 amino acids
C76H128N18O18S
Standard
Sequence
INWLKLGKMVIDAL
Physicochemical Analysis
1614.00 Da
8.59
0.76
0.55
0.0542
0.87
0.56
0.35
15.79
167.14
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
589.84
-0.68
20.0
20.0
55.0
113.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068153 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Cryptococcus neoformans
11.0 μM
EC50
PaperCharacterization of two novel polyfunctional mastoparan peptides from the venom of the social wasp Polybia paulista PMID19463874
RECORD: Rec_0088412 VERIFIED: YES
Provenance & Taxonomy
Parachartergus vespiceps testaceus [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Chemotactic Cytotoxic Hemolytic
Mycobacterium abscessus
80 at 12.5 % inhibition at μM
Intracellular/ex vivo mycobacterial growth inhibition
PMID28108242;30974767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28108242/
RECORD: Rec_0088874 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Chemotactic Cytotoxic Hemolytic
Staphylococcus aureus (Gram-positive)
Qualitative functional evidence
PMID15150833;19463874;30974767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15150833/
RECORD: Rec_0110701 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 64.3%, C 35.7% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Inflammatory
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0118728 VERIFIED: YES
Provenance & Taxonomy
Parachartergus vespiceps testaceus [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Chemotactic Cytotoxic Hemolytic
Escherichia coli
Qualitative functional evidence
PMID28108242;30974767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28108242/
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