Peptide Database

Peptide NameAgaricus blazei polypeptide (ABp)

Function Ontology

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC130H171N35O57

DescriptionStandard

        EHEEHEEHEEHEPEDDPNSSEESYW
    

Molecular Weight3135.95 Da

Isoelectric Point (pI)4.06

Net Charge (pH 7.0)-12.79

Net Charge (pH 7.4) -13.18

Charge Density (pH 7.0) -0.5114

GRAVY Index-2.78

Hydrophobic Moment 0.18

Boman Index-0.46

Instability Index91.02

Aliphatic Index 0.00

Aromaticity 0.0800

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1483.56

LogP -16.10

H-bond Donors 47.0

H-bond Acceptors 48.0

Rotatable Bonds 101.0

Heavy Atoms 222.0

Ring Count 9.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398336 VERIFIED: YES

Provenance & Taxonomy

OrganismAgaricus blazei [Fungus]

FamilyFungal polypeptide

Tax ID79798

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-aging Antioxidant

TargetICR mice (In vivo)

MethodCell proliferation assay; Western blot; Immunofluorescence; qRT-PCR; Behavioral assay; Enzyme activity assay