‹ ›
MYP_151412
← PREVIOUS NEXT → BACK
Basic Information
Defensin 1
Antimicrobial
Standard
39 amino acids
C199H300N58O48S7
Standard
Sequence
GGYYCPFFQDKCHRHCRSFGRKAGYCGGFLKKTCICVMK
Physicochemical Analysis
4497.33 Da
9.42
6.87
6.46
0.1761
-0.34
0.80
-0.07
47.97
30.00
0.1795
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1715.03
-15.49
68.0
64.0
147.0
312.0
10.0
39.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0039061 VERIFIED: YES
Provenance & Taxonomy
Castor bean tick [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
constitutive: not induced and called guard AMPs. Sequence analysis: APD analysis reveals that this sequence is similar (94.87%) to Ir-Def1 C=G: 15%, K: 13%. GRAVY: -0.34; mol Wt: 4497.38; mol formula: C199H300N58O48S7; mol ex coeff: 4845. Chemical modification: C5-C26, C12-C34 and C16-C36
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
>250 μM
MIC
PaperThe immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus.
RECORD: Rec_0047030 VERIFIED: YES
Provenance & Taxonomy
Castor bean tick [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
constitutive: not induced and called guard AMPs. Sequence analysis: APD analysis reveals that this sequence is similar (94.87%) to Ir-Def1 C=G: 15%, K: 13%. GRAVY: -0.34; mol Wt: 4497.38; mol formula: C199H300N58O48S7; mol ex coeff: 4845. Chemical modification: C5-C26, C12-C34 and C16-C36
Bio-Activity Profile
Antimicrobial
M. maritypicum
0.98 μM
MIC
PaperThe immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus.
RECORD: Rec_0143013 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID15691006 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15691006/
RECORD: Rec_0187078 VERIFIED: YES
Provenance & Taxonomy
Castor bean tick [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
constitutive: not induced and called guard AMPs. Sequence analysis: APD analysis reveals that this sequence is similar (94.87%) to Ir-Def1 C=G: 15%, K: 13%. GRAVY: -0.34; mol Wt: 4497.38; mol formula: C199H300N58O48S7; mol ex coeff: 4845. Chemical modification: C5-C26, C12-C34 and C16-C36
Bio-Activity Profile
Antimicrobial
Micrococcus luteus
0.031 μM
MIC
PaperThe immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus.
RECORD: Rec_0187498 VERIFIED: YES
Provenance & Taxonomy
Castor bean tick [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
constitutive: not induced and called guard AMPs. Sequence analysis: APD analysis reveals that this sequence is similar (94.87%) to Ir-Def1 C=G: 15%, K: 13%. GRAVY: -0.34; mol Wt: 4497.38; mol formula: C199H300N58O48S7; mol ex coeff: 4845. Chemical modification: C5-C26, C12-C34 and C16-C36
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
1.95 μM
MIC
PaperThe immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus.
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2