Peptide Database

Peptide NameCentrocin 2 (EeCentrocin 2) [Cleaved into: Centrocin 2; heavy chain; Centrocin 2; light chain]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC575H924N160O176S8

DescriptionStandard

        MMIKIAVVLCAVMATSMVFANDVKEQELADLLDLLISEEVSSPDDAVAESWGHKLRSSWNKVKHAVKKGAGYASGACRVLGHSPQEARAKVLEAFPEMKESDLDEEQVGKYCAVAHAIHGR
    

Molecular Weight13150.97 Da

Isoelectric Point (pI)5.69

Net Charge (pH 7.0)-4.07

Net Charge (pH 7.4) -4.62

Charge Density (pH 7.0) -0.0336

GRAVY Index-0.09

Hydrophobic Moment 0.61

Boman Index0.05

Instability Index46.27

Aliphatic Index 90.33

Aromaticity 0.0496

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5361.57

LogP -50.73

H-bond Donors 187.0

H-bond Acceptors 185.0

Rotatable Bonds 446.0

Heavy Atoms 919.0

Ring Count 16.0

Amide Bonds 125.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341113 VERIFIED: YES

Provenance & Taxonomy

OrganismEchinus esculentus [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria