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MYP_151402
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Basic Information
PvD1, Defensin D1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
47 amino acids
C222H346N72O73S8
Standard
Sequence
KTCENLADTYKGPCFTTGSCDDHCKNKEHLRSGRCRDDFRCWCTKNC
Physicochemical Analysis
5448.08 Da
8.20
1.86
1.42
0.0396
-1.15
0.50
-0.37
37.24
18.72
0.0851
6990.00
7490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2396.19
-31.94
93.0
85.0
181.0
375.0
8.0
49.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040712 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Animal]
Defensin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID29076508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29076508/
RECORD: Rec_0147922 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Animal]
Defensin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID29076508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29076508/
RECORD: Rec_0158533 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
Defensin
3885
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
PaperPubMed PMID 18786582 PMID18786582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18786582/
RECORD: Rec_0335429 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Animal]
Defensin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: MDA-MB-231
0.82±0.14 μM
IC50
PMID29076508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29076508/
RECORD: Rec_0371555 VERIFIED: NO
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium solani, Fusarium laterithium, Rizoctonia solani and, Fusarium oxysporum
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