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MYP_151392
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Basic Information
Z8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C132H186N34O22
Standard
Sequence
AWKKWAKAWKWAKAKWWAKAA
Physicochemical Analysis
2601.10 Da
10.78
6.79
6.59
0.3233
-0.87
0.59
-0.03
-11.95
38.10
0.2857
33000.00
33000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
922.20
0.50
35.0
29.0
81.0
188.0
12.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002834 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 22057278 PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
RECORD: Rec_0022567 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
Meth A
19 μM
EC50
PaperRelative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
RECORD: Rec_0073878 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 66.7%, E 0.0%, T 19.0%, C 14.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0082145 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
RECORD: Rec_0135581 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MT-1
14 μM
EC50
PaperPubMed PMID: 22057278 PMID22057278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22057278/
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