Peptide Database

Peptide NameSLAY-screened peptide P3160

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC86H147N23O16S

DescriptionStandard

        IYIRVFCLLIIRIR
    

Molecular Weight1791.30 Da

Isoelectric Point (pI)10.76

Net Charge (pH 7.0)2.75

Net Charge (pH 7.4) 2.53

Charge Density (pH 7.0) 0.1964

GRAVY Index1.77

Hydrophobic Moment 0.58

Boman Index0.30

Instability Index23.04

Aliphatic Index 215.71

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 647.55

LogP 0.59

H-bond Donors 26.0

H-bond Acceptors 20.0

Rotatable Bonds 59.0

Heavy Atoms 126.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097972 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/