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MYP_151357
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Basic Information
EBR28[Q2A]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C72H119N17O16S
Standard
Sequence
YALLIRMIYKNI
Physicochemical Analysis
1510.88 Da
9.70
1.76
1.55
0.1464
0.86
0.56
0.27
65.52
170.83
0.1667
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
554.89
-0.10
20.0
19.0
50.0
106.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0207898 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
P4 cells
PaperA novel short peptide is a specific inhibitor of the human immunodeficiency virus type 1 integrase PMID12054767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054767/
RECORD: Rec_0353429 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:Inhibition of 3′-end processing catalyzed by integrase
8 μM
IC50
PaperA novel short peptide is a specific inhibitor of the human immunodeficiency virus type 1 integrase PMID12054767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054767/
RECORD: Rec_0382600 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 41.7%, E 0.0%, T 25.0%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
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