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MYP_151321
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Basic Information
Neuropeptide FF
Cardiovascular
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
8 amino acids
C54H75N13O11
Standard
Sequence
FLFQPQRF
Physicochemical Analysis
1082.25 Da
9.75
0.76
0.56
0.0950
-0.11
0.47
0.07
56.90
48.75
0.3750
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
406.31
-1.13
13.0
12.0
32.0
78.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036308 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
FMRFamide related peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
Evidence URLhttps://www.uniprot.org/uniprotkb/NPFF_HUMAN/entry
RECORD: Rec_0133950 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Rattus norvegicus [Animal]
9913, 10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0175034 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Neuropeptide FF
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Growth regulation Development regulation Receptor modulation
M2 macrophage-associated genes IL-4 receptor
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
RECORD: Rec_0189578 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Neuropeptide FF
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Receptor modulation Feeding regulator
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuropeptide FF (Rattus norvegicus): PMID 18295932 PMID18295932 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18295932/
RECORD: Rec_0233893 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Neuropeptide FF
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Receptor modulation
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
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