Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC624H1018N170O206S5

DescriptionStandard

        MTVKNKLGLVTRVGATAALALGLGAAVVPSASASAAAPVVSVTPATGLSDGATVTLNASGLTPGTVYHVGQCAFVEDGQYGCNKATALDVVADASGAVNTKITVKQSFEAVVGSATTPWGTVDCKVTACQVGLGSDKGEGGGQLISFS
    

Molecular Weight14358.10 Da

Isoelectric Point (pI)5.63

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0098

GRAVY Index0.42

Hydrophobic Moment 0.47

Boman Index0.25

Instability Index12.23

Aliphatic Index 90.95

Aromaticity 0.0405

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5915.99

LogP -79.12

H-bond Donors 208.0

H-bond Acceptors 211.0

Rotatable Bonds 462.0

Heavy Atoms 1005.0

Ring Count 13.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168395 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. CB02400 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal