Peptide Database

Peptide Name[D-Ala7]-angiotensin(1-7)

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC39H60N12O11

DescriptionStandard

        DRVYIHA
    

Molecular Weight872.97 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0218

GRAVY Index-0.29

Hydrophobic Moment 0.43

Boman Index-0.07

Instability Index4.66

Aliphatic Index 111.43

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 386.03

LogP -2.32

H-bond Donors 14.0

H-bond Acceptors 12.0

Rotatable Bonds 26.0

Heavy Atoms 62.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140786 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Vasoactive Signaling peptide

TargetMAS1 (Mouse)

Activity0.3 nM

MethodIC50