Peptide Database

Peptide NameBrevinin-2HS1

Function Ontology

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Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC117H194N32O30

DescriptionStandard

        GLWNTIKEAGKKFALNLLDKIR
    

Molecular Weight2528.99 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1255

GRAVY Index-0.27

Hydrophobic Moment 0.66

Boman Index-0.03

Instability Index6.62

Aliphatic Index 115.45

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1037.20

LogP -6.62

H-bond Donors 36.0

H-bond Acceptors 33.0

Rotatable Bonds 89.0

Heavy Atoms 179.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078614 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops granulosus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli TOP10

Activity3.59 OD_ID (dimensionless)

MethodMe^x pooled intracellular-expression growth assay; E. coli TOP10; OD_ID at 4.5 h; rank 1861; Wald/BH adjusted p=0.2195