Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC495H802N152O135S11

DescriptionStandard

        MCHRVQYKKPGLQAVTHTTNRRAYDKMSRFIVFAFIVAMCIAHSLAAPAPEALEASVVRQKRLTCDLLSFEAKGFAANHSLCAAHCLAIGRKGGACQNGVCVCRS
    

Molecular Weight11395.32 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)8.86

Net Charge (pH 7.4) 8.26

Charge Density (pH 7.0) 0.0844

GRAVY Index0.17

Hydrophobic Moment 0.88

Boman Index0.05

Instability Index44.53

Aliphatic Index 82.86

Aromaticity 0.0667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4588.96

LogP -48.51

H-bond Donors 170.0

H-bond Acceptors 160.0

Rotatable Bonds 376.0

Heavy Atoms 793.0

Ring Count 15.0

Amide Bonds 111.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0020712 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctes rhinoceros [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal