Peptide Database

Peptide NameRabbit neutrophil defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC149H248N46O44S6

DescriptionStandard

        ATCYCRIGHCTILESLSGVCEISGRLYRLCCR
    

Molecular Weight3580.23 Da

Isoelectric Point (pI)8.35

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0571

GRAVY Index0.43

Hydrophobic Moment 0.69

Boman Index0.04

Instability Index32.65

Aliphatic Index 97.50

Aromaticity 0.0625

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1457.91

LogP -15.72

H-bond Donors 61.0

H-bond Acceptors 53.0

Rotatable Bonds 117.0

Heavy Atoms 245.0

Ring Count 3.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121384 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli TOP10

Activity4.18 OD_ID (dimensionless)

MethodMe^x pooled intracellular-expression growth assay; E. coli TOP10; OD_ID at 4.5 h; rank 6096; Wald/BH adjusted p=1