Peptide Database

Peptide NameSBP1

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC65H111N19O15S2

DescriptionStandard

        LVCHPAVPALLCAR
    

Molecular Weight1462.83 Da

Isoelectric Point (pI)8.08

Net Charge (pH 7.0)0.83

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0591

GRAVY Index1.38

Hydrophobic Moment 0.19

Boman Index0.36

Instability Index71.79

Aliphatic Index 146.43

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 514.62

LogP -2.69

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 41.0

Heavy Atoms 101.0

Ring Count 3.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228628 VERIFIED: YES

Provenance & Taxonomy

OrganismPlasmodium falciparum [Protist]

FamilySBP1

Tax ID5833

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide3-12

Bio-Activity Profile

Function

Antimicrobial Antimalarial Antiparasitic

TargetPlasmodium falciparum 3D7

Activity1.7 μM

MethodIC50; Microscopy (Giemsa staining)

RECORD: Rec_0381388 VERIFIED: YES