MYP_151062
Labyrinthopeptin A2
Antimicrobial
Standard
18 amino acids
C85H120N20O28S4
Standard
SDWSLWECCSTGSLFACC
1998.24 Da
4.05
-2.58
-2.84
-0.1431
0.51
0.19
0.27
66.71
48.89
0.1667
11000.00
11250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
765.35
-8.52
32.0
30.0
59.0
137.0
5.0
17.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0156374
VERIFIED: YES
Provenance & Taxonomy
Actinomadura namibiensis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
This peptide contains a special amino acid labionin at positions 1, 4, 8, 10, 13, and 17 (represented with S before modification). Labs 1,4 and labs 10, 13 are connected via a carbon-carbon bond, while labs 4, 8 and labs 13, 17 form normal thioether bonds. In addition, a disulfide bond occurs between C9 and C18. Note that Labionin is a triamino acid with a 2S,4S,8R configuration, and consists of a central quarternary carbon atom with a lanthionine motif and an unusual methylene bridge, which establishes a covalent link to a further amino acid moiety
Bio-Activity Profile
the proliferation of diverse enveloped viruses, including dengue virus, Zika virus (ZIKV), West Nile virus (WNV), hepatitis C virus (HCV), chikungunya virus, Kaposiâs sarcoma-associated herpesvirus, cytomegalovirus
RECORD: Rec_0265414
VERIFIED: YES
Provenance & Taxonomy
Actinomadura namibiensis [Bacterium]; Bacteria [Bacterium]
2; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0360749
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 55.6%, E 0.0%, T 27.8%, C 16.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0364019
VERIFIED: YES
Provenance & Taxonomy
Actinomadura namibiensis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0408792
VERIFIED: YES
Provenance & Taxonomy
Actinomadura namibiensis [Animal]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial
HSV