Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC389H624N122O109S11

DescriptionStandard

        MSMPFIRPNGLVRFLRQPDATAAAAGSDAQKCWNLLGKCRQRCSRKESVYVYCTNGKMCCVKPRCSQNEANCPFVKWRGTA
    

Molecular Weight9106.58 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)9.42

Net Charge (pH 7.4) 9.07

Charge Density (pH 7.0) 0.1163

GRAVY Index-0.45

Hydrophobic Moment 0.71

Boman Index-0.15

Instability Index42.97

Aliphatic Index 51.85

Aromaticity 0.0864

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3769.58

LogP -43.59

H-bond Donors 140.0

H-bond Acceptors 130.0

Rotatable Bonds 298.0

Heavy Atoms 631.0

Ring Count 14.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201111 VERIFIED: NO

Provenance & Taxonomy

OrganismNeotoma lepida [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal