Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

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Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC137H215N33O42S6

DescriptionStandard

        GVPCAESCVYIPCTITALFGCSCKDKVCYN
    

Molecular Weight3188.76 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0100

GRAVY Index0.63

Hydrophobic Moment 0.28

Boman Index0.24

Instability Index38.43

Aliphatic Index 74.67

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1180.75

LogP -12.18

H-bond Donors 46.0

H-bond Acceptors 48.0

Rotatable Bonds 97.0

Heavy Atoms 218.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372208 VERIFIED: YES

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)