Peptide Database

Peptide NameHepcidin

Function Ontology

—

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC89H145N31O22S9

DescriptionStandard

        GCRFCCGCCPRMRGCGVCCKF
    

Molecular Weight2289.88 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)3.68

Net Charge (pH 7.4) 3.36

Charge Density (pH 7.0) 0.1752

GRAVY Index0.53

Hydrophobic Moment 0.40

Boman Index-0.03

Instability Index7.47

Aliphatic Index 13.81

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 848.25

LogP -10.62

H-bond Donors 39.0

H-bond Acceptors 35.0

Rotatable Bonds 72.0

Heavy Atoms 151.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0394916 VERIFIED: YES

Provenance & Taxonomy

OrganismDichotomyctere nigroviridis [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)