Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length239 amino acids

Chemical FormulaC1183H1839N303O334S13

DescriptionStandard

        MSVEAVCSQLSQSCHCHSSLFLMFTVTARIDDKTGIDYSLVGPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTASIAYHKAGALVFEVTDAMIPKETGFKLETSVFSAFIPQVSSLMYPNMPMKFRLSAPTAPFLTIGPGGISFQPVVDAQAYAILPNSSLAPLFLLSLVRRMQNLMNVLTSSILLPRLNGENLLEGMGKLEHPPLRLLHPSGPAH
    

Molecular Weight26066.93 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.81

Net Charge (pH 7.4) -1.52

Charge Density (pH 7.0) -0.0034

GRAVY Index0.19

Hydrophobic Moment 0.68

Boman Index0.18

Instability Index43.97

Aliphatic Index 91.05

Aromaticity 0.0962

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216288 VERIFIED: NO

Provenance & Taxonomy

OrganismCatharus ustulatus (Russet-backed thrush) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria