Peptide Database

Peptide NameDefensin-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC441H709N129O136S8

DescriptionStandard

        MKVLVLLAAIFLVAIQAQADPLPARTEEALDQEQFGAEDQDVPVDFTGDEGSALRAAGLRSIFTCYCRRGTCRSSEQRKGRCGFSIMYNLCCR
    

Molecular Weight10250.65 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0166

GRAVY Index-0.06

Hydrophobic Moment 0.62

Boman Index-0.02

Instability Index50.92

Aliphatic Index 81.94

Aromaticity 0.0753

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4295.05

LogP -46.15

H-bond Donors 156.0

H-bond Acceptors 143.0

Rotatable Bonds 342.0

Heavy Atoms 714.0

Ring Count 10.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234755 VERIFIED: NO

Provenance & Taxonomy

OrganismTupaia chinensis [Animal]

FamilyDefensin

Tax ID246437

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal