Peptide Database

Peptide NameLantibiotic Flvalpha.d

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC356H567N99O123S8

DescriptionStandard

        MNKNPIYRSEEEAKDIACGNVAAELDENSQALDAINGAGWKQTIVCTIAQGTVGCLVSYGLGNGGYCCTYTVECSKTCNK
    

Molecular Weight8458.42 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-3.56

Net Charge (pH 7.4) -3.90

Charge Density (pH 7.0) -0.0445

GRAVY Index-0.21

Hydrophobic Moment 0.53

Boman Index0.05

Instability Index46.05

Aliphatic Index 72.00

Aromaticity 0.0625

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3611.04

LogP -45.78

H-bond Donors 129.0

H-bond Acceptors 128.0

Rotatable Bonds 282.0

Heavy Atoms 586.0

Ring Count 7.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128651 VERIFIED: NO

Provenance & Taxonomy

OrganismRuminococcus flavefaciens [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Synergistic peptide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0138354 VERIFIED: YES