Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC757H1178N222O218S6

DescriptionStandard

        MARVQFKQREFTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDEMAVGSHAKGYNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYESAVLRAHHEVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight17069.20 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.46

Hydrophobic Moment 0.75

Boman Index-0.06

Instability Index40.87

Aliphatic Index 74.90

Aromaticity 0.0927

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7114.92

LogP -69.95

H-bond Donors 251.0

H-bond Acceptors 234.0

Rotatable Bonds 571.0

Heavy Atoms 1203.0

Ring Count 29.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396977 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage T7 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic