Peptide Database

Peptide NameBeta-defensin 119 (Beta-defensin 120) (Beta-defensin 19) (DEFB-19) (Beta-defensin 20) (DEFB-20) (Defensin; beta 119) (Defensin; beta 120) (ESC42-RELA)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC432H690N120O121S10

DescriptionStandard

        MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCLQSYMRISISGKEENTDWSYEKQWPRLP
    

Molecular Weight9821.48 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.13

Charge Density (pH 7.0) 0.0539

GRAVY Index-0.29

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index80.42

Aliphatic Index 85.95

Aromaticity 0.0952

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3920.28

LogP -34.25

H-bond Donors 144.0

H-bond Acceptors 137.0

Rotatable Bonds 329.0

Heavy Atoms 683.0

Ring Count 15.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219382 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found