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MYP_150828
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Basic Information
S471-503
Antimicrobial
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Binding inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Standard
33 amino acids
C184H260N40O50S
Standard
Sequence
ALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFEL
Physicochemical Analysis
3864.34 Da
4.37
-1.22
-1.43
-0.0368
0.17
0.43
0.27
3.41
88.48
0.2424
12950.00
12950.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1440.57
-8.33
51.0
50.0
113.0
275.0
11.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160766 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
Virus-derived peptide
694009;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
SARS coronavirus (Virus entry); Vero
41.6 μM
Plaque assay
PaperScreening and identification of linear B-cell epitopes and entry-blocking peptide of severe acute respiratory syndrome (SARS)-associated coronavirus using synthetic overlapping peptide library. | Hu H, Li L, Kao RY, Kou B, Wang Z, Zhang L, Zhang H, Hao Z, Tsui WH, Ni A, Cui L, Fan B, Guo F, Rao S, Jiang C, Li Q, Sun M, He W, Liu G. | J Comb Chem. 2005 | PMID:16153058 PMID16153058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16153058/
RECORD: Rec_0217962 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-SARS-CoV Binding inhibition
SARS-CoV (Severe acute respiratory syndrome) | Vero cells
41.6 μM
EC50
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperScreening and identification of linear B-cell epitopes and entry-blocking peptide of severe acute respiratory syndrome (SARS)-associated coronavirus using synthetic overlapping peptide library. | Hu H, Li L, Kao RY, Kou B, Wang Z, Zhang L, Zhang H, Hao Z, Tsui WH, Ni A, Cui L, Fan B, Guo F, Rao S, Jiang C, Li Q, Sun M, He W, Liu G. | J Comb Chem. 2005 Sep-Oct;7(5):648-56. | DOI:10.1021/cc0500607 | PMID:16153058 PMID16153058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16153058/
RECORD: Rec_0252733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV
PMID16153058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16153058/
RECORD: Rec_0260814 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human Influenza A Virus H1N1
PMID16153058 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16153058/
RECORD: Rec_0279224 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
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