MYP_150825
LC-AMP-I1
Anticancer
Antimicrobial
Standard
25 amino acids
C140H235N39O35S2
Standard
GRMQEFIKKLKAYLRKMKEKFSQIS
3088.73 Da
10.38
5.76
5.54
0.2303
-0.88
0.69
-0.31
32.55
66.40
0.1200
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1263.11
-8.65
45.0
43.0
115.0
216.0
3.0
26.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0205366
VERIFIED: YES
Provenance & Taxonomy
Lycosa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from spider venom via HPLC. Whole sequence was then obtained by comparingd the detected sequence with the transcriptome data. Sequence analysis: APD analysis reveals that this sequence is 44% similar to Meucin-24 K: 24%. GRAVY: -0.876; mol Wt: 3088.76; mol formula: C140H235N39O35S2; mol ex coeff: 1490. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
mouse breast cancer cells 4T1
20 μM
IC50
RECORD: Rec_0242487
VERIFIED: YES
Provenance & Taxonomy
Lycosa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from spider venom via HPLC. Whole sequence was then obtained by comparingd the detected sequence with the transcriptome data. Sequence analysis: APD analysis reveals that this sequence is 44% similar to Meucin-24 K: 24%. GRAVY: -0.876; mol Wt: 3088.76; mol formula: C140H235N39O35S2; mol ex coeff: 1490. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Pseudomonas aeruginosa CGMCC 1.596
5-10 μM
MIC
RECORD: Rec_0256339
VERIFIED: YES
Provenance & Taxonomy
Lycosa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from spider venom via HPLC. Whole sequence was then obtained by comparingd the detected sequence with the transcriptome data. Sequence analysis: APD analysis reveals that this sequence is 44% similar to Meucin-24 K: 24%. GRAVY: -0.876; mol Wt: 3088.76; mol formula: C140H235N39O35S2; mol ex coeff: 1490. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Klebsiella pneumoniae
10 μM
MIC
RECORD: Rec_0323815
VERIFIED: YES
Provenance & Taxonomy
Lycosa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
isolated from spider venom via HPLC. Whole sequence was then obtained by comparingd the detected sequence with the transcriptome data. Sequence analysis: APD analysis reveals that this sequence is 44% similar to Meucin-24 K: 24%. GRAVY: -0.876; mol Wt: 3088.76; mol formula: C140H235N39O35S2; mol ex coeff: 1490. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Anticancer
E. faecium
2.5 μM
MIC
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