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MYP_150816
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Basic Information
Moricin-like peptide C2 (Gm-mlpC2; Insects, animals; Predicted)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
38 amino acids
C178H305N57O46
Standard
Sequence
KVPIGAIKKGGKIIKKGLGVLGAAGTAHEVYNHVRNRQ
Physicochemical Analysis
3979.68 Da
10.73
6.93
6.61
0.1824
-0.25
0.80
0.00
-0.19
102.63
0.0263
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1675.54
-16.32
58.0
55.0
139.0
281.0
4.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0340652 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fusarium oxysporum mycelia
8 μM
MIC
PMID18207081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18207081/
RECORD: Rec_0343605 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum
8 μM
MIC
PaperThe discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella
RECORD: Rec_0367264 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Inactive: A.niger
>150 μM
MIC
PaperThe discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella
RECORD: Rec_0369640 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0411289 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fusarium graminearum spores
1 μM
MIC
PMID18207081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18207081/
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