Peptide Database

Peptide NameDermaseptin

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC372H605N101O123S3

DescriptionStandard

        MAFIKKSLFLVLFLGLVSLSICEEEKRENEEENNQEDDEQSEEKRALWKSLLKNVGKAAGKAALNAVTDMVNQGEQ
    

Molecular Weight8556.58 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.74

Charge Density (pH 7.0) -0.0721

GRAVY Index-0.52

Hydrophobic Moment 0.66

Boman Index-0.09

Instability Index53.41

Aliphatic Index 89.87

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3705.35

LogP -36.84

H-bond Donors 124.0

H-bond Acceptors 121.0

Rotatable Bonds 307.0

Heavy Atoms 599.0

Ring Count 5.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084358 VERIFIED: NO

Provenance & Taxonomy

OrganismCallimedusa duellmani [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal