Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC188H312N58O48S6

DescriptionStandard

        ISNPVTCLRSGAICHPGFCPRRYKHIGTCGLSVIKCCKKP
    

Molecular Weight4345.24 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)6.87

Net Charge (pH 7.4) 6.47

Charge Density (pH 7.0) 0.1718

GRAVY Index0.04

Hydrophobic Moment 0.48

Boman Index0.01

Instability Index57.87

Aliphatic Index 75.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1674.67

LogP -17.91

H-bond Donors 65.0

H-bond Acceptors 63.0

Rotatable Bonds 138.0

Heavy Atoms 300.0

Ring Count 8.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124207 VERIFIED: YES

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)