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MYP_150726
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Basic Information
Puroindoline-A (38-44)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
7 amino acids
C67H76N16O8
Standard
Sequence
WRWWKWW
Physicochemical Analysis
1233.42 Da
11.00
1.76
1.55
0.2513
-1.84
0.68
0.00
90.40
0.00
0.7143
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
404.79
4.32
17.0
10.0
31.0
91.0
10.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0277614 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa
250 μg/mL
IC50
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0288374 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Sheep erythrocytes: No hemolysis up tp 500 μg/ml
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0367142 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
8 μg/mL
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0379854 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
r=D-Arg; w=D-Trp
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
NIH 3T3
250 μg/mL
IC50
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0390747 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 9027
16 μg/mL
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
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