Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC172H296N62O46S7

DescriptionStandard

        VRNPQSCHRNKGICVPIRCPGNMRQIGTCLGPPVKCCR
    

Molecular Weight4193.03 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.41

Charge Density (pH 7.0) 0.1779

GRAVY Index-0.40

Hydrophobic Moment 0.47

Boman Index-0.18

Instability Index72.24

Aliphatic Index 63.95

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1742.20

LogP -22.05

H-bond Donors 65.0

H-bond Acceptors 61.0

Rotatable Bonds 134.0

Heavy Atoms 287.0

Ring Count 6.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280671 VERIFIED: YES

Provenance & Taxonomy

OrganismBubalus bubalis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)