Peptide Database

Peptide NameTHP-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC112H169N31O29S4

DescriptionStandard

        LFCKGGSCHFGGCPSHLIKVGSCFG
    

Molecular Weight2541.99 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)1.89

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0757

GRAVY Index0.56

Hydrophobic Moment 0.43

Boman Index0.32

Instability Index56.27

Aliphatic Index 58.40

Aromaticity 0.1200

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 923.02

LogP -10.26

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 80.0

Heavy Atoms 176.0

Ring Count 6.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0405684 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)