Peptide Database

Peptide NameSLAY-screened peptide P5103

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC93H135N25O37

DescriptionStandard

        QVTNDSGSYYNSNFGVSLDQ
    

Molecular Weight2195.21 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.1120

GRAVY Index-0.84

Hydrophobic Moment 0.29

Boman Index-0.04

Instability Index2.25

Aliphatic Index 48.50

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1047.88

LogP -16.17

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 70.0

Heavy Atoms 155.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382890 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/