Peptide Database

Peptide NameProTx-III [ mu-TRTX-Tp1a]

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Venom / Toxin ▸ General toxin ▸ huwentoxin-1 family

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC162H251N51O44S6

DescriptionStandard

        DCLKFGWKCNPRNDKCCSGLKCGSNHNWCKLHI
    

Molecular Weight3809.43 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)3.87

Net Charge (pH 7.4) 3.47

Charge Density (pH 7.0) 0.1173

GRAVY Index-0.72

Hydrophobic Moment 0.44

Boman Index-0.16

Instability Index26.91

Aliphatic Index 47.27

Aromaticity 0.0909

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1554.09

LogP -16.96

H-bond Donors 59.0

H-bond Acceptors 56.0

Rotatable Bonds 126.0

Heavy Atoms 263.0

Ring Count 8.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423622 VERIFIED: YES

Provenance & Taxonomy

OrganismThrixopelma pruriens [Animal]

Familyhuwentoxin-1 family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-17; 9-22; 16-29

Bio-Activity Profile

Function

Toxin Venom huwentoxin-1 family Ion channel inhibitor Pathogenesis-associated