Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC467H755N135O124S11

DescriptionStandard

        MKFLFLFLVILLAMDPVLSAECWMDGKCRLVCKNDEDSVIRCANRKRCCVPSRYLTVQPMTVERMEPWTVPHTPKPVKQKTRSRPGSRHYG
    

Molecular Weight10597.54 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.62

Net Charge (pH 7.4) 7.19

Charge Density (pH 7.0) 0.0838

GRAVY Index-0.29

Hydrophobic Moment 0.61

Boman Index-0.10

Instability Index58.90

Aliphatic Index 74.84

Aromaticity 0.0769

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4153.70

LogP -35.47

H-bond Donors 152.0

H-bond Acceptors 145.0

Rotatable Bonds 345.0

Heavy Atoms 737.0

Ring Count 19.0

Amide Bonds 94.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0094154 VERIFIED: NO

Provenance & Taxonomy

OrganismOdobenus rosmarus divergens [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0256792 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin