Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC385H599N107O120S12

DescriptionStandard

        MKTLTVAVAVAVVLAFIWQESAATFHGAQQPEEAVSNEDPAADPQETPVDSWMMPSNRQKRGMKCKFCCNCCNLNGCGVCCDF
    

Molecular Weight9031.30 Da

Isoelectric Point (pI)4.83

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.88

Charge Density (pH 7.0) -0.0419

GRAVY Index-0.07

Hydrophobic Moment 0.43

Boman Index0.06

Instability Index50.09

Aliphatic Index 58.80

Aromaticity 0.0723

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3622.15

LogP -40.86

H-bond Donors 127.0

H-bond Acceptors 130.0

Rotatable Bonds 290.0

Heavy Atoms 624.0

Ring Count 14.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140267 VERIFIED: NO

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence