Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length465 amino acids

Chemical FormulaC2362H3685N615O663S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAVLEKELTKVKVPDISGDFHIRHVGKVHYELSRLDLRSFHLPYSRISLLPSLGLQVSISNAFASVDGNWRVKLYFIRDHGSFDLRVENVYIKINLNLGKDSSGKPTINTSDCSTHISKVWVHFSGKLGWLYNLFYGAVEHRFRKILESKVASLPLFPQVCDMVANSVHTELQPYAQTLPVTSKIDDMVGIDYALVAPPAATAQSLDVDLKGEFYSLAHRSAVPFSPLPLALPPDHDHMVYFGVSSYFLNTASFAYHTAGALVFEITDSMIPKDVEFHLTTSTFSAFIPELEKMYPNTPMKLRLSTPSPPFLSITPEGLSLKPVVDIQAYAILPSDQLAPLFLLSLVSKVSAVISVSSGHIVGNLTVGRMKLSLKHSDVGTFQVRTLQSMMNIYTSNILLPNLNERLGQGFPLPLPDRIKLHNIIVRFQQDSLMLGADVHYEPR
    

Molecular Weight51690.03 Da

Isoelectric Point (pI)7.33

Net Charge (pH 7.0)1.15

Net Charge (pH 7.4) -0.18

Charge Density (pH 7.0) 0.0025

GRAVY Index0.07

Hydrophobic Moment 0.64

Boman Index0.13

Instability Index39.29

Aliphatic Index 102.04

Aromaticity 0.0946

Extinction Coeff. Reduced 41830.00

Extinction Coeff. Oxidized 41955.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072930 VERIFIED: NO

Provenance & Taxonomy

OrganismOreotrochilus melanogaster [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria