Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length190 amino acids

Chemical FormulaC949H1510N268O252S10

DescriptionStandard

        PKTPPLAHEPMLLLAVTEFVANSAAFTYFTAGALRRNFSSDMLPRKFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFVLNIDANMTGKPTITRNRLGGTVRLTGGARATLPALCRAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPCHVP
    

Molecular Weight21026.44 Da

Isoelectric Point (pI)10.13

Net Charge (pH 7.0)11.36

Net Charge (pH 7.4) 10.95

Charge Density (pH 7.0) 0.0598

GRAVY Index-0.04

Hydrophobic Moment 0.55

Boman Index0.05

Instability Index52.62

Aliphatic Index 87.84

Aromaticity 0.0789

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8187.15

LogP -97.84

H-bond Donors 286.0

H-bond Acceptors 278.0

Rotatable Bonds 665.0

Heavy Atoms 1479.0

Ring Count 42.0

Amide Bonds 203.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010707 VERIFIED: NO

Provenance & Taxonomy

OrganismRhadina sibilatrix [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria