Peptide Database

Peptide NameNisin, C-terminal

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC213H370N62O70S8

DescriptionStandard

        MDLISVSKKDSGVSPRITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK
    

Molecular Weight5176.11 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0707

GRAVY Index0.16

Hydrophobic Moment 0.32

Boman Index0.06

Instability Index25.95

Aliphatic Index 76.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2116.09

LogP -29.65

H-bond Donors 80.0

H-bond Acceptors 83.0

Rotatable Bonds 175.0

Heavy Atoms 353.0

Ring Count 3.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124808 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis subsp. lactis [Bacterium]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0411864 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis subsp. lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence