Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC385H634N120O114S7

DescriptionStandard

        MKLLLAFAIISFLAQTTQGSWESRRCWNDIGRCRRICRSNEKNHSQCTNKQKCCSNSFVKSGLKSSSPKSVIIAIPSNLN
    

Molecular Weight8992.34 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)9.53

Net Charge (pH 7.4) 9.16

Charge Density (pH 7.0) 0.1191

GRAVY Index-0.38

Hydrophobic Moment 0.77

Boman Index-0.12

Instability Index57.51

Aliphatic Index 75.62

Aromaticity 0.0625

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3868.01

LogP -49.01

H-bond Donors 143.0

H-bond Acceptors 132.0

Rotatable Bonds 308.0

Heavy Atoms 626.0

Ring Count 10.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008238 VERIFIED: NO

Provenance & Taxonomy

OrganismMonodelphis domestica [Animal]

FamilyDefensin

Tax ID13616

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence