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MYP_150426
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Basic Information
V681
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C138H227N35O34
Standard
Sequence
KWKSFLKTFKSAVKTVLHTALKAISS
Physicochemical Analysis
2920.49 Da
10.70
5.84
5.58
0.2247
0.10
0.67
0.06
5.45
93.85
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1133.02
-8.86
42.0
41.0
100.0
207.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007896 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa H188
20.2 μg/mL
MIC
PaperRational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem. 2005 Apr 1;280(13):12316-29. doi: 10.1074/jbc.M413406200. PMID: 15677462. PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
RECORD: Rec_0009648 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperRational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem. 2005 Apr 1;280(13):12316-29. doi: 10.1074/jbc.M413406200. PMID: 15677462. PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
RECORD: Rec_0014573 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
D-Ser at 11
Bio-Activity Profile
Hemolytic
Human red blood cells
15.6 μg/mL
MHC
PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
RECORD: Rec_0016148 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
D-Ser at 11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus SAP0017
2.5 μg/mL
MIC
PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
RECORD: Rec_0021606 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
D-Ser at 11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis C625
6.4 μg/mL
MIC
PMID15677462 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15677462/
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