Peptide Database

Peptide NameDermaseptin PS4

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC375H615N101O124S3

DescriptionStandard

        MDILKKSIFLVLFLGLVSLSICEEEKRENEDEEKQEDDEQSEEKRALWKTLLKHVGKAAGKAALNAVTDMVNQGEQ
    

Molecular Weight8618.69 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-6.39

Net Charge (pH 7.4) -6.71

Charge Density (pH 7.0) -0.0841

GRAVY Index-0.57

Hydrophobic Moment 0.65

Boman Index-0.11

Instability Index56.67

Aliphatic Index 93.68

Aromaticity 0.0395

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3705.38

LogP -34.25

H-bond Donors 125.0

H-bond Acceptors 122.0

Rotatable Bonds 311.0

Heavy Atoms 603.0

Ring Count 5.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0098187 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal