Peptide Database

Peptide NameHIV-1 Rev (34-50)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC102H181N53O26S

DescriptionStandard

        TRQARRNRRRRWRERQRGC
    

Molecular Weight2597.93 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.39

Net Charge (pH 7.4) 8.18

Charge Density (pH 7.0) 0.4416

GRAVY Index-2.98

Hydrophobic Moment 0.44

Boman Index-1.39

Instability Index182.51

Aliphatic Index 5.26

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1408.71

LogP -19.29

H-bond Donors 57.0

H-bond Acceptors 36.0

Rotatable Bonds 92.0

Heavy Atoms 182.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424778 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsConjugation with Alexa 488 at glycyl cysteine sequence

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

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