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MYP_150346
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Basic Information
HIV-1 Rev (34-50)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C102H181N53O26S
Standard
Sequence
TRQARRNRRRRWRERQRGC
Physicochemical Analysis
2597.93 Da
12.00
8.39
8.18
0.4416
-2.98
0.44
-1.39
182.51
5.26
0.0526
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1408.71
-19.29
57.0
36.0
92.0
182.0
2.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0063270 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Fluorophore labeling
C-term detail: Alexa 488 labeling at glycyl cysteine sequence
Bio-Activity Profile
Cell-penetrating peptide
CHO-K1; HeLa; Jurkat
Fluorescence-based uptake assay
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0097599 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0210861 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
RECORD: Rec_0289044 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Alexa 488 labeling at glycyl cysteine sequence
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0415124 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Alexa Fluor conjugation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
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