Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length234 amino acids

Chemical FormulaC1199H1864N310O325S5

DescriptionStandard

        QGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHEAGALVFEITEAMIPKEARFSLDTSVFSAFIPQLEEKYPNMPMKFRLSTPTAPFLTIGPGGISFQPIVDIQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVQFLQSIMNILTSNVLLPHLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVRFQPR
    

Molecular Weight25981.83 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)1.22

Net Charge (pH 7.4) 0.73

Charge Density (pH 7.0) 0.0052

GRAVY Index0.27

Hydrophobic Moment 0.61

Boman Index0.18

Instability Index42.69

Aliphatic Index 105.85

Aromaticity 0.1111

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 8940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237817 VERIFIED: NO

Provenance & Taxonomy

OrganismAgelaius phoeniceus (Red-winged blackbird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria