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MYP_150316
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Basic Information
Cecropin LSer-Cec4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
40 amino acids
C183H311N61O53
Standard
Sequence
GWLKKIGKKIERVGQHTRDASIQAIGIAQQAANVAATARG
Physicochemical Analysis
4213.80 Da
11.07
4.85
4.59
0.1212
-0.32
0.94
-0.04
14.98
93.00
0.0250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1883.21
-21.76
66.0
59.0
147.0
297.0
3.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037185 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
11 μM
MIC
RECORD: Rec_0050206 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
LSer
13632
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PaperAntimicrob Agents Chemother. 2015 May;59(5):2508-14 | http://www.ncbi.nlm.nih.gov/pubmed/25666157 PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0143884 VERIFIED: YES
Provenance & Taxonomy
Common green [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0172185 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
13632
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
1.1 μM
MIC
PaperAntimicrobial peptides expressed in medicinal maggots of the blow fly Lucilia sericata show combinatorial activity against bacteria. PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0189398 VERIFIED: YES
Provenance & Taxonomy
Lucilia cuprina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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