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MYP_150309
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Basic Information
Afusin-C
Antimicrobial
Antimicrobial ▸ Antifungal
Standard
38 amino acids
C163H245N45O55S8
Standard
Sequence
SICCSFPDPWGGLCCEDHCSYIGKPGGQCSDKGVCTCN
Physicochemical Analysis
3971.48 Da
4.66
-2.53
-2.91
-0.0665
-0.14
0.48
0.09
18.81
38.42
0.0789
6990.00
7490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1566.92
-21.21
60.0
62.0
122.0
271.0
8.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046017 VERIFIED: YES
Provenance & Taxonomy
Aspergillus fumigatus [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Gram-positive bacteria, including Staphylococcus aureus and Micrococcus luteus
MIC/MBC antimicrobial assay
PaperRecombinant AfusinC, an anionic fungal CSαβ defensin from Aspergillus fumigatus, exhibits antimicrobial activity against gram-positive bacteria. DOI:10.1371/journal.pone.0205509 PMID30308015
RECORD: Rec_0099061 VERIFIED: YES
Provenance & Taxonomy
Aspergillus fumigatus [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Streptococcus pyogenes ATCC 12344
64 μg/mL
MIC
PaperDiscovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSalphabeta defensins PMID30308015
RECORD: Rec_0100420 VERIFIED: YES
Provenance & Taxonomy
Aspergillus fumigatus [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis DSM 10
16 μg/mL
MIC
PaperDiscovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSalphabeta defensins PMID30308015
RECORD: Rec_0170787 VERIFIED: YES
Provenance & Taxonomy
Aspergillus fumigatus [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Yersinia mollaretii DSM 18520
64 μg/mL
MIC
PaperDiscovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSalphabeta defensins PMID30308015
RECORD: Rec_0171055 VERIFIED: YES
Provenance & Taxonomy
Aspergillus fumigatus [Fungus]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
8 μg/mL
MIC
PaperDiscovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSalphabeta defensins PMID30308015
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