Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC138H204N34O38S2

DescriptionStandard

        AAAQHLCGSHLVDALYLVCGEKGFFYTP
    

Molecular Weight3011.43 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-1.05

Net Charge (pH 7.4) -1.37

Charge Density (pH 7.0) -0.0374

GRAVY Index0.49

Hydrophobic Moment 0.34

Boman Index0.32

Instability Index7.16

Aliphatic Index 90.71

Aromaticity 0.1429

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1122.22

LogP -8.26

H-bond Donors 40.0

H-bond Acceptors 41.0

Rotatable Bonds 92.0

Heavy Atoms 212.0

Ring Count 7.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169188 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus keta [Animal]

FamilyInsulin

Tax ID8018

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0257604 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus keta [Animal]

FamilyInsulin

Tax ID8018

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0257661 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/