Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length283 amino acids

Chemical FormulaC1414H2254N398O396S5

DescriptionStandard

        TNPGFVVRITQTGLDYARQQGIAILEKELAQLKLPDVSGKSGKVRYSFSRLRILSFRLPRSGITPISNVGLQVSISNAFAELNGDWRVKFLFIKGHGSFNLKVENANMKIILRLGSDTTGRPTISTSGCSAHISKVRVRFSGKLGWLYNLFHRVIERKLRKNLESKVCDNVAKSVHNELQKQVRTLPVTARIDDKIGVDYSLVAPPRATPKSLDLNLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMVSGTSG
    

Molecular Weight31325.78 Da

Isoelectric Point (pI)10.09

Net Charge (pH 7.0)18.00

Net Charge (pH 7.4) 17.36

Charge Density (pH 7.0) 0.0636

GRAVY Index-0.13

Hydrophobic Moment 0.87

Boman Index0.02

Instability Index31.07

Aliphatic Index 92.65

Aromaticity 0.0919

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295038 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodinocichla rosea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria