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MYP_150207
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Basic Information
NS3proC-C15
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
15 amino acids
C69H113N19O20
Standard
Sequence
PRPISYLKGSSGGPL
Physicochemical Analysis
1528.75 Da
10.01
1.96
1.90
0.1304
-0.40
0.32
0.07
26.89
78.00
0.0667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
607.99
-7.03
22.0
22.0
46.0
108.0
4.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0083415 VERIFIED: YES
Provenance & Taxonomy
Hepatitis C virus [Virus]
Virus-derived peptide
3052230;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibitor Replication inhibitor
Hepatitis C virus (Translation); Huh7
5 μM
ELISA
PaperInhibition of the interaction between NS3 protease and HCV IRES with a small peptide: a novel therapeutic strategy. | Ray U, Roy CL, Kumar A, Mani P, Joseph AP, Sudha G, Sarkar DP, Srinivasan N, Das S. | Mol Ther. 2013 | PMID:22910295 PMID22910295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22910295/
RECORD: Rec_0098315 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0414557 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV)
PMID22910295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22910295/